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41.
In this paper, a decision model is presented for the sales of software product to determine the profit and marketing policy under the influence of promotional efforts. The paper focuses on dependence of the optimal profit on the promotional efforts when there is diffusion effect of demand on the sales function. An elaborate optimization policy considering the dynamic nature of production cost function is proposed and numerical example is illustrated. The paper also studies the behavior of the future profit and its impact on profit maximization model by considering the constant price during the entire planning horizon. The experimental results greatly help us to identify the contributions of each selected parameter and its weight. Some conclusions, limitations of this study and future direction are also discussed.  相似文献   
42.
Hypertension, a well known risk factor for various cardiovascular, peripheral vascular and renal events is an important public health challenge. Renin angiotensin system (RAS) being the most vital pathogenic mechanism of hypertension is mediated by a key component; the angiotensin converting enzyme (ACE). The present study was aimed to know the relationship of ACE gene polymorphism and the possible risk of development of hypertension in south Indian population. The study included 101 clinically diagnosed hypertensive patients without any associated disease condition and 81 age and sex matched apparently healthy controls. Genotyping was performed using a polymerase chain reaction, (PCR) amplification of the intron 16 fragment harboring the 287 bp Alu repeat sequence. Three possible genotypes D/D, I/I homozygous and I/D heterozygous were analyzed where the D/D genotypes corresponds to higher ACE levels (D-Deletion, I-Insertion). The PCR products were separated on 2 % agarose gel. Statistical analysis was performed using SPSS.15 software program. We found a significance in frequency of D/D genotype in the hypertensive patients compared to the control group (p = 0.0005, odd’s ratio = 4.157). This suggested that ACE (D/D) genotypes are more prone for the development of hypertension. This is relatively a pilot study; but nevertheless may assist in identifying the pathophysiological cause of hypertension.  相似文献   
43.
The vital task of the libraries attached to the educational institutions of higher learning is the collection development of information resources as per the requirements of the users. The Central Library of IITs have long been recognized their responsibility to support the study and research of their parent institutions with the rich collection development of information resources both in print as well as electronic format to cater the needs of the academic communities as per the multi-disciplinary and diverse academic program of the respective institutions where greater emphasis on collection of serials, the essential and integral component of updated scholarly communication. The study provides a vivid picture about the current status of serials collection in the libraries attached to the Premier Institutions of India in the field of science and technology to boost up the academic performances.  相似文献   
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Abstract

The purpose of this study was to examine student perceptions of the learning environment in their program major and general education classrooms. The participants were 870 undergraduate students majoring in engineering, fine arts, education, economics and nursing programs at a university in Thailand. We found significant differences in the perceptions of the classroom learning environment across various disciplines. Engineering and economics students perceived the learning environment in general education classrooms as more cooperative than the learning environment in program major classrooms. Fine arts and nursing students perceived greater involvement among students in the program major classrooms than in the general education classrooms. Our findings contribute to the body of research on inter-disciplinary differences in classroom learning environments in universities and the ways in which these differences may impact student learning outcomes.  相似文献   
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Abstract

One of the major impediments for diversification of groundnut (Arachis Hypogaea L.) as food crop is aflatoxin contamination. The study was conducted with an objective to assess the adoption gaps in aflatoxin management practices of groundnut (AMPG) and the farmer's characteristics influencing these gaps. The study used an expost-facto research design and multi-stage random sampling. The data were collected from 180 respondents through interview schedule. For measuring adoption gap, knowledge of AMPG and perception of groundnut quality suitable scales were developed. The data were subjected to multiple regression analysis to know the characteristics, which influenced the adoption gaps in AMPG. The majority of farmers were in high adoption gap category, as most of the farmers had not adopted the harvest and post-harvest management practices. Farmers' characteristics such as knowledge, market orientation and innovativeness influenced the adoption gap significantly. These three variables put together explained 58% of variation in adoption gap. Based on the results, it is suggested to formulate strategies to increase the knowledge of farmers through various extension approaches. If the knowledge on AMPG is improved the adoption gaps can be reduced. The maiden research effort, shed light on the socio-economic dimensions of aflatoxin contamination and constraints for aflatoxin management at farmers' level. The study has significance for the policy makers, extension departments and groundnut farmers for production of quality groundnut.  相似文献   
47.
Research on the adoption of systems for big data analytics has drawn enormous attention in Information Systems research. This study extends big data analytics adoption research by examining the effects of system characteristics on the attitude of managers towards the usage of big data analytics systems. A research model has been proposed in this study based on an extensive review of literature pertaining to the Technology Acceptance Model, with further validation by a survey of 150 big data analytics users. Results of this survey confirm that characteristics of the big data analytics system have significant direct and indirect effects on belief in the benefits of big data analytics systems and perceived usefulness, attitude and adoption. Moreover, there are mediation effects that exist among the system characteristics, benefits of big data analytics systems, perceived usefulness and the attitude towards using big data analytics system. This study expands the existing body of knowledge on the adoption of big data analytics systems, and benefits big data analytics providers and vendors while helping in the formulation of their business models.  相似文献   
48.
We present design, characterization, and testing of an inexpensive, sheath-flow based microfluidic device for three-dimensional (3D) hydrodynamic focusing of cells in imaging flow cytometry. In contrast to other 3D sheathing devices, our device hydrodynamically focuses the cells in a single-file near the bottom wall of the microchannel that allows imaging cells with high magnification and low working distance objectives, without the need for small device dimensions. The relatively large dimensions of the microchannels enable easy fabrication using less-precise fabrication techniques, and the simplicity of the device design avoids the need for tedious alignment of various layers. We have characterized the performance of the device with 3D numerical simulations and validated these simulations with experiments of hydrodynamic focusing of a fluorescently dyed sample fluid. The simulations show that the width and the height of the 3D focused sample stream can be controlled independently by varying the heights of main and side channels of the device, and the flow rates of sample and sheath fluids. Based on simulations, we also provide useful guidelines for choosing the device dimensions and flow rates for focusing cells of a particular size. Thereafter, we demonstrate the applicability of our device for imaging a large number of RBCs using brightfield microscopy. We also discuss the choice of the region of interest and camera frame rate so as to image each cell individually in our device. The design of our microfluidic device makes it equally applicable for imaging cells of different sizes using various other imaging techniques such as phase-contrast and fluorescence microscopy.  相似文献   
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Solitons emerge as non-perturbative solutions of non-linear wave equations in classical and quantum theories. These are non-dispersive and localised packets of energy — remarkable properties for solutions of non-linear differential equations. In the presence of such objects, the solutions of Dirac equation lead to the curious phenomenon of ‘fractional fermion number’. Under normal conditions the fermion number takes strictly integral values. In this article, we describe this accidental discovery and its manifestation in polyacetylene chains, which has led to the development of organic conductors. (left) Kumar Rao is a Postdoctoral Fellow at PRL, Ahmedabad. He is interested in particle physics phenomenology as probed in particle colliders and formal aspects of quantum field theory. (right) Narendra Sahu is currently a postdoctoral fellow at Lancaster University, UK. His main research area includes Cosmology and Astroparticle physics. Currently he is working on dark matter and matter anti-matter asymmetry of the universe. (center) P K Panigrahi’s research interests are in the area of quantum computation, solitons in Bose Einstein condensates & nonlinear optical media. He is also deeply interested in science education and derives pleasure from long weekend walks.  相似文献   
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